Thymidine phosphorylase

BE0001995ProteinEscherichia coli (strain K12)deoA

The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for... It is acted on by 1 drug in DrugBank.

Gene name
deoA
UniProtKB entry
P07650Swiss-Prot
Residues / weight
440 residues · 47,207 Da
Also known as
2.4.2.4 · TdRPase · tpp · ttg

Resolves to

Protein
UniProtP07650UniProt nameTYPH_ECOLI
Gene
NCBI Gene948901GenBank537222
Pharmacology
KEGGecj:JW4345
Structure
PDB1AZYPDB1OTPPDB1TPT
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
8GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
9+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Thymidine phosphorylase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In