UDP-glucose 6-dehydrogenase

BE0002000ProteinStreptococcus pyogeneshasB

Catalyzes the formation of UDP-glucuronic acid which is required for capsular hyaluronic acid synthesis. It is acted on by 2 drugs in DrugBank.

Gene name
hasB
UniProtKB entry
P0C0F4Swiss-Prot
Residues / weight
402 residues · 45,483 Da
Also known as
1.1.1.22 · UDP-Glc dehydrogenase

Resolves to

Protein
UniProtP0C0F4UniProt nameUDG_STRPY
Gene
GenBank295189
Structure
PDB1DLIPDB1DLJPDB1LTY
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on UDP-glucose 6-dehydrogenase, and which indications are they being tested in?

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