Delta-aminolevulinic acid dehydratase

BE0002002ProteinEscherichia coli (strain K12)hemB

Catalyzes an early step in the biosynthesis of tetrapyrroles. It is acted on by 3 drugs in DrugBank.

Gene name
hemB
UniProtKB entry
P0ACB2Swiss-Prot
Residues / weight
324 residues · 35,624 Da
Also known as
4.2.1.24 · ALAD · ncf · Porphobilinogen synthase

Resolves to

Protein
UniProtP0ACB2UniProt nameHEM2_ECOLI
Gene
NCBI Gene945017GenBank450371
Pharmacology
KEGGecj:JW0361
Structure
PDB1B4EPDB1I8JPDB1L6S
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Delta-aminolevulinic acid dehydratase, and which indications are they being tested in?

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