Coenzyme A biosynthesis bifunctional protein CoaBC

BE0002020ProteinEscherichia coli (strain K12)coaBC

Catalyzes two sequential steps in the biosynthesis of coenzyme A. It is acted on by 2 drugs in DrugBank.

Gene name
coaBC
UniProtKB entry
P0ABQ0Swiss-Prot
Residues / weight
406 residues · 43,438 Da
Also known as
dfp · DNA/pantothenate metabolism flavoprotein · Phosphopantothenoylcysteine synthetase/decarboxylase · PPCS-PPCDC

Resolves to

Protein
UniProtP0ABQ0UniProt nameCOABC_ECOLI
Gene
NCBI Gene949047
Pharmacology
KEGGecj:JW5642
Structure
PDB1U7UPDB1U7WPDB1U7Z
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Coenzyme A biosynthesis bifunctional protein CoaBC, and which indications are they being tested in?

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