Cytochrome c-552

BE0002028ProteinEscherichia coli (strain K12)nrfA

Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process (PubMed:11863430, PubMed:18311941, PubMed:20629638, PubMed:9593308). It is acted on by 2 drugs in DrugBank.

Gene name
nrfA
UniProtKB entry
P0ABK9Swiss-Prot
Cellular location
Periplasm
Residues / weight
478 residues · 53,703 Da
Also known as
1.7.2.2 · Ammonia-forming cytochrome c nitrite reductase · Cytochrome c nitrite reductase

Resolves to

Protein
UniProtP0ABK9UniProt nameNRFA_ECOLI
Gene
NCBI Gene948571GenBank853826
Pharmacology
KEGGecj:JW4031
Structure
PDB1GU6PDB2RDZPDB2RF7
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Cytochrome c-552, and which indications are they being tested in?

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