Beta-lactamase SHV-2

BE0002029ProteinEscherichia colibla

This enzyme hydrolyzes cefotaxime, ceftazidime and other broad spectrum cephalosporins. It is acted on by 2 drugs in DrugBank.

Gene name
bla
UniProtKB entry
P0A9Z7Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
286 residues · 31,254 Da
Also known as
3.5.2.6 · SHV-2A · shv2

Resolves to

Protein
UniProtP0A9Z7UniProt nameBLA2_ECOLX
Gene
GenBank5002314
Pharmacology
KEGGag:AAD37413
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
1Clinical trialTrials of drugs acting on it, by phase and status
Sign in
3GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
5+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Beta-lactamase SHV-2, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In