Ribosomal small subunit pseudouridine synthase A

BE0002034ProteinEscherichia coli (strain K12)rsuA

Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA. It is acted on by 2 drugs in DrugBank.

Gene name
rsuA
UniProtKB entry
P0AA43Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
231 residues · 25,865 Da
Also known as
16S pseudouridylate 516 synthase · 16S rRNA pseudouridine(516) synthase · 5.4.99.19 · rRNA pseudouridylate synthase A · rRNA-uridine isomerase A

Resolves to

Protein
UniProtP0AA43UniProt nameRSUA_ECOLI
Gene
NCBI Gene945378
Pharmacology
KEGGecj:JW2171
Structure
PDB1KSKPDB1KSLPDB1KSV
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Ribosomal small subunit pseudouridine synthase A, and which indications are they being tested in?

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