Glucarate dehydratase

BE0002036ProteinEscherichia coli (strain K12)gudD

Catalyzes the dehydration of glucarate or L-idarate to 5-keto-4-deoxy-D-glucarate (5-kdGluc) (PubMed:9772162). It is acted on by 4 drugs in DrugBank.

Gene name
gudD
UniProtKB entry
P0AES2Swiss-Prot
Residues / weight
446 residues · 49,141 Da
Also known as
4.2.1.40 · D-glucarate dehydratase · GDH · ygcX

Resolves to

Protein
UniProtP0AES2UniProt nameGUDD_ECOLI
Gene
NCBI Gene947258GenBank1786182
Pharmacology
KEGGecj:JW2758
Structure
PDB1EC7PDB1EC8PDB1EC9
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
3GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
14+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Glucarate dehydratase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In