Glycine betaine/proline betaine-binding periplasmic protein

BE0002045ProteinEscherichia coli (strain K12)proX

Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. It is acted on by 3 drugs in DrugBank.

Gene name
proX
UniProtKB entry
P0AFM2Swiss-Prot
Cellular location
Periplasm
Residues / weight
330 residues · 36,022 Da
Also known as
GBBP · Glycine betaine-binding periplasmic protein · proU

Resolves to

Protein
UniProtP0AFM2UniProt namePROX_ECOLI
Gene
NCBI Gene947165GenBank147373
Pharmacology
KEGGecj:JW2654
Structure
PDB1R9LPDB1R9Q
Drugs

What you can answer from here — as of May 03, 2025

3DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Glycine betaine/proline betaine-binding periplasmic protein, and which indications are they being tested in?

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