Nucleoside-specific channel-forming protein tsx

BE0002061ProteinEscherichia coli (strain K12)tsx

Functions as a substrate-specific channel for nucleosides and deoxynucleosides (PubMed:2458926, PubMed:3276691, PubMed:791677). It is acted on by 1 drug in DrugBank.

Gene name
tsx
UniProtKB entry
P0A927Swiss-Prot
Cellular location
Cell outer membrane
Residues / weight
294 residues · 33,589 Da
Also known as
nupA

Resolves to

Protein
UniProtP0A927UniProt nameTSX_ECOLI
Gene
NCBI Gene946242
Pharmacology
KEGGecj:JW0401
Structure
PDB1TLWPDB1TLYPDB1TLZ
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Nucleoside-specific channel-forming protein tsx, how selective are they, and which programs against it are still in active trials?

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