2-iminobutanoate/2-iminopropanoate deaminase

BE0002076ProteinEscherichia coli (strain K12)ridA

Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell. It is acted on by 1 drug in DrugBank.

Gene name
ridA
UniProtKB entry
P0AF93Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
128 residues · 13,611 Da
Also known as
3.5.99.10 · Enamine/imine deaminase · yjgF

Resolves to

Protein
UniProtP0AF93UniProt nameRIDA_ECOLI
Gene
NCBI Gene948771
Pharmacology
KEGGecj:JW5755
Structure
PDB1QU9
Drugs

What you can answer from here — as of September 04, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 2-iminobutanoate/2-iminopropanoate deaminase, and which indications are they being tested in?

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