Laminin subunit alpha-5

BE0002103ProteinHumansLAMA5

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is acted on by 1 drug in DrugBank.

Gene name
LAMA5
UniProtKB entry
O15230Swiss-Prot
Cellular location
Secreted, extracellular space, extracellular matrix, basement membrane
Residues / weight
3,695 residues · 399,733 Da
Also known as
KIAA0533 · KIAA1907 · Laminin-10 subunit alpha · Laminin-11 subunit alpha · Laminin-15 subunit alpha

Resolves to

Protein
UniProtO15230UniProt nameLAMA5_HUMAN
Gene
HGNCHGNC:6485NCBI Gene3911GenBank12274842GeneCardsLAMA5
Pharmacology
KEGGhsa:3911
Structure
PDB5XAUPDB7CEC
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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14GO termsFunction, process and component, as structured annotations
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7Pfam domainsDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Laminin subunit alpha-5, and which indications are they being tested in?

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