Laminin subunit beta-1

BE0002106ProteinHumansLAMB1

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is acted on by 1 drug in DrugBank.

Gene name
LAMB1
UniProtKB entry
P07942Swiss-Prot
Cellular location
Secreted, extracellular space, extracellular matrix, basement membrane
Residues / weight
1,786 residues · 198,037 Da
Also known as
Laminin B1 chain · Laminin-1 subunit beta · Laminin-10 subunit beta · Laminin-12 subunit beta · Laminin-2 subunit beta

Resolves to

Protein
UniProtP07942UniProt nameLAMB1_HUMAN
Gene
HGNCHGNC:6486NCBI Gene3912GenBank186913GeneCardsLAMB1
Pharmacology
KEGGhsa:3912
Structure
PDB5XAUPDB7CECPDB8DMK
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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18GO termsFunction, process and component, as structured annotations
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5Pfam domainsDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Laminin subunit beta-1, and which indications are they being tested in?

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