Laminin subunit alpha-1

BE0002108ProteinHumansLAMA1

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is acted on by 1 drug in DrugBank.

Gene name
LAMA1
UniProtKB entry
P25391Swiss-Prot
Cellular location
Secreted, extracellular space, extracellular matrix, basement membrane
Residues / weight
3,075 residues · 337,081 Da
Also known as
LAMA · Laminin A chain · Laminin-1 subunit alpha · Laminin-3 subunit alpha · S-LAM alpha

Resolves to

Protein
UniProtP25391UniProt nameLAMA1_HUMAN
Gene
HGNCHGNC:6481NCBI Gene284217GenBank34226GeneCardsLAMA1
Pharmacology
KEGGhsa:284217
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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18GO termsFunction, process and component, as structured annotations
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6Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Laminin subunit alpha-1, and which indications are they being tested in?

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