Cytokine receptor common subunit beta

BE0002115ProteinHumansCSF2RB

Cell surface receptor that plays a role in immune response and controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. It is acted on by 5 drugs in DrugBank.

Gene name
CSF2RB
UniProtKB entry
P32927Swiss-Prot
Cellular location
Membrane
Residues / weight
897 residues · 97,335 Da
Also known as
CDw131 · GM-CSF/IL-3/IL-5 receptor common beta subunit · IL3RB · IL5RB

Resolves to

Protein
UniProtP32927UniProt nameIL3RB_HUMAN
Gene
HGNCHGNC:2436NCBI Gene1439GenBank487425GeneCardsCSF2RB
Pharmacology
KEGGhsa:1439
Structure
PDB1C8PPDB1EGJPDB1GH7
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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19+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cytokine receptor common subunit beta, how selective are they, and which programs against it are still in active trials?

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