Neuroendocrine convertase 1

BE0002125ProteinHumansPCSK1

Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. It is acted on by 1 drug in DrugBank.

Gene name
PCSK1
UniProtKB entry
P29120Swiss-Prot
Cellular location
Cytoplasmic vesicle, secretory vesicle
Residues / weight
753 residues · 84,151 Da
Also known as
3.4.21.93 · NEC 1 · NEC1 · PC1 · Prohormone convertase 1

Resolves to

Protein
UniProtP29120UniProt nameNEC1_HUMAN
Gene
HGNCHGNC:8743NCBI Gene5122GenBank35318GeneCardsPCSK1
Pharmacology
IUPHAR/GtoPdb2382KEGGhsa:5122
Structure
PDB9FICPDB9FIDPDB9FIE
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
2Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
7GO termsFunction, process and component, as structured annotations
Sign in
4Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
13+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Neuroendocrine convertase 1, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In