Collagen alpha-1(II) chain

BE0002140ProteinHumansCOL2A1

Type II collagen is specific for cartilaginous tissues. It is acted on by 1 drug in DrugBank.

Gene name
COL2A1
UniProtKB entry
P02458Swiss-Prot
Cellular location
Secreted, extracellular space, extracellular matrix
Residues / weight
1,487 residues · 141,785 Da
Also known as
Alpha-1 type II collagen

Resolves to

Protein
UniProtP02458UniProt nameCO2A1_HUMAN
Gene
HGNCHGNC:2200NCBI Gene1280GenBank29516GeneCardsCOL2A1
Pharmacology
KEGGhsa:1280
Structure
PDB1U5MPDB2FSEPDB2SEB
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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78+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Collagen alpha-1(II) chain, how selective are they, and which programs against it are still in active trials?

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