Glutamate decarboxylase 2

BE0002159ProteinHumansGAD2

Catalyzes the production of GABA.

Gene name
GAD2
UniProtKB entry
Q5VZ30TrEMBL
Residues / weight
585 residues · 65,411 Da
Also known as
4.1.1.15 · 65 kDa glutamic acid decarboxylase · Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa) · Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa), isoform CRA_b · Glutamate decarboxylase 65 kDa isoform

Resolves to

Protein
UniProtQ5VZ30UniProt nameQ5VZ30_HUMAN
Gene
NCBI Gene2572GenBank55662653
Pharmacology
KEGGhsa:2572

What you can answer from here — as of May 03, 2025

11GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Glutamate decarboxylase 2, and which indications are they being tested in?

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