Glutamate decarboxylase 1

BE0002165ProteinHumansGAD1

Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor.

Gene name
GAD1
UniProtKB entry
Q8IVA8TrEMBL
Residues / weight
594 residues · 66,916 Da
Also known as
4.1.1.15 · Brain, 67kDa · Glutamate decarboxylase 1 (Brain, 67kDa)

Resolves to

Protein
UniProtQ8IVA8UniProt nameQ8IVA8_HUMAN
Gene
NCBI Gene2571GenBank23138819
Pharmacology
KEGGhsa:2571

What you can answer from here — as of May 03, 2025

4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Glutamate decarboxylase 1, and which indications are they being tested in?

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