Glutamate decarboxylase 2

BE0002173ProteinHumansGAD65

Catalyzes the production of GABA. It is acted on by 2 drugs in DrugBank.

Gene name
GAD65
UniProtKB entry
Q9UGI5TrEMBL
Residues / weight
419 residues · 47,344 Da
Also known as
4.1.1.15 · 65 kDa glutamic acid decarboxylase · EC 4.1.1.15 · Glutamate decarboxylase 65 kDa isoform · Glutamic acid decarboxylase

Resolves to

Protein
UniProtQ9UGI5UniProt nameQ9UGI5_HUMAN
Gene
GenBank6562440
Drugs

What you can answer from here — as of May 03, 2025

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glutamate decarboxylase 2, how selective are they, and which programs against it are still in active trials?

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