Choline transporter-like protein 2

BE0002183ProteinHumansSLC44A2

Choline/H+ antiporter, mainly in mitochondria (PubMed:10677542, PubMed:20665236, PubMed:23651124, PubMed:33789160). It is acted on by 1 drug in DrugBank.

Gene name
SLC44A2
UniProtKB entry
Q8IWA5Swiss-Prot
Cellular location
Cell membrane
Residues / weight
706 residues · 80,123 Da
Also known as
CTL2 · Solute carrier family 44 member 2

Resolves to

Protein
UniProtQ8IWA5UniProt nameCTL2_HUMAN
Gene
HGNCHGNC:17292NCBI Gene57153GenBank6996444GeneCardsSLC44A2
Pharmacology
KEGGhsa:57153
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Choline transporter-like protein 2, how selective are they, and which programs against it are still in active trials?

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