Protein-glutamine gamma-glutamyltransferase 5

BE0002236ProteinHumansTGM5

Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. It is acted on by 1 drug in DrugBank.

Gene name
TGM5
UniProtKB entry
O43548Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
720 residues · 80,777 Da
Also known as
2.3.2.13 · TG(X) · TGase X · TGase-5 · TGMX

Resolves to

Protein
UniProtO43548UniProt nameTGM5_HUMAN
Gene
HGNCHGNC:11781NCBI Gene9333GenBank2895530GeneCardsTGM5
Pharmacology
KEGGhsa:9333
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
3GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
6+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Protein-glutamine gamma-glutamyltransferase 5, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In