Glutamine--tRNA ligase

BE0002242ProteinHumansQARS1

Glutamine--tRNA ligase (PubMed:26869582). It is acted on by 1 drug in DrugBank.

Gene name
QARS1
UniProtKB entry
P47897Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
775 residues · 87,798 Da
Also known as
6.1.1.18 · GlnRS · Glutaminyl-tRNA synthetase · QARS

Resolves to

Protein
UniProtP47897UniProt nameSYQ_HUMAN
Gene
HGNCHGNC:9751NCBI Gene5859GenBank558586GeneCardsQARS1
Pharmacology
KEGGhsa:5859
Structure
PDB4R3ZPDB4YE6PDB4YE8
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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5Pfam domainsDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glutamine--tRNA ligase, how selective are they, and which programs against it are still in active trials?

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