Protein-glutamine gamma-glutamyltransferase Z

BE0002245ProteinHumansTGM7

Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. It is acted on by 1 drug in DrugBank.

Gene name
TGM7
UniProtKB entry
Q96PF1Swiss-Prot
Residues / weight
710 residues · 79,941 Da
Also known as
TG(Z) · TGase Z · TGase-7 · TGZ · Transglutaminase Z

Resolves to

Protein
UniProtQ96PF1UniProt nameTGM7_HUMAN
Gene
HGNCHGNC:30790NCBI Gene116179GenBank15425755GeneCardsTGM7
Pharmacology
KEGGhsa:116179
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Protein-glutamine gamma-glutamyltransferase Z, how selective are they, and which programs against it are still in active trials?

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