S-formylglutathione hydrolase

BE0002283ProteinHumansESD

Serine hydrolase involved in the detoxification of formaldehyde. It is acted on by 2 drugs in DrugBank.

Gene name
ESD
UniProtKB entry
P10768Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
282 residues · 31,463 Da
Also known as
3.1.2.12 · Esterase D · FGH · Methylumbelliferyl-acetate deacetylase

Resolves to

Protein
UniProtP10768UniProt nameESTD_HUMAN
Gene
HGNCHGNC:3465NCBI Gene2098GenBank182265GeneCardsESD
Pharmacology
KEGGhsa:2098
Structure
PDB3FCX
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
7GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
19+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on S-formylglutathione hydrolase, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In