Protein peroxidase GPX7

BE0002289ProteinHumansGPX7

Acts as an endoplasmic reticulum (ER) thiol peroxidase that maintains ER redox homeostasis and supports oxidative protein folding (PubMed:32719007). It is acted on by 1 drug in DrugBank.

Gene name
GPX7
UniProtKB entry
Q96SL4Swiss-Prot
Cellular location
Endoplasmic reticulum
Residues / weight
187 residues · 20,996 Da
Also known as
CL683 · GPx-7 · GPX6 · GSHPx-7

Resolves to

Protein
UniProtQ96SL4UniProt nameGPX7_HUMAN
Gene
HGNCHGNC:4559NCBI Gene2882GenBank25990366GeneCardsGPX7
Pharmacology
KEGGhsa:2882
Structure
PDB2P31
Drugs

What you can answer from here — as of June 19, 2026

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Protein peroxidase GPX7, how selective are they, and which programs against it are still in active trials?

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