Glutaredoxin-2, mitochondrial

BE0002292ProteinHumansGLRX2

Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. It is acted on by 1 drug in DrugBank.

Gene name
GLRX2
UniProtKB entry
Q9NS18Swiss-Prot
Cellular location
Mitochondrion
Residues / weight
164 residues · 18,052 Da
Also known as
GRX2

Resolves to

Protein
UniProtQ9NS18UniProt nameGLRX2_HUMAN
Gene
HGNCHGNC:16065NCBI Gene51022GenBank9507250GeneCardsGLRX2
Pharmacology
KEGGhsa:51022
Structure
PDB2CQ9PDB2FLSPDB2HT9
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
3GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
15+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Glutaredoxin-2, mitochondrial, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In