Diacylglycerol kinase gamma

BE0002296ProteinHumansDGKG

Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:8034597). It is acted on by 1 drug in DrugBank.

Gene name
DGKG
UniProtKB entry
P49619Swiss-Prot
Cellular location
Membrane
Residues / weight
791 residues · 89,123 Da
Also known as
2.7.1.107 · DAG kinase gamma · DAGK3 · DGK-gamma · Diglyceride kinase gamma

Resolves to

Protein
UniProtP49619UniProt nameDGKG_HUMAN
Gene
HGNCHGNC:2853NCBI Gene1608GenBank516758GeneCardsDGKG
Pharmacology
KEGGhsa:1608
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
12GO termsFunction, process and component, as structured annotations
Sign in
4Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
7+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Diacylglycerol kinase gamma, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In