Glycine cleavage system H protein, mitochondrial

BE0002302ProteinHumansGCSH

The glycine cleavage system catalyzes the degradation of glycine. It is acted on by 3 drugs in DrugBank.

Gene name
GCSH
UniProtKB entry
P23434Swiss-Prot
Cellular location
Mitochondrion
Residues / weight
173 residues · 18,884 Da
Also known as
Lipoic acid-containing protein

Resolves to

Protein
UniProtP23434UniProt nameGCSH_HUMAN
Gene
HGNCHGNC:4208NCBI Gene2653GenBank184348GeneCardsGCSH
Pharmacology
KEGGhsa:2653
Structure
PDB8UGOPDB8V0JPDB9C19
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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3Metabolic reactionsDrug transformations it catalyses, substrate to product
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glycine cleavage system H protein, mitochondrial, how selective are they, and which programs against it are still in active trials?

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