N-arachidonyl glycine receptor

BE0002304ProteinHumansGPR18

G protein-coupled receptor (GPCR) that plays a role in diverse physiological processes particularly within the immune and nervous systems (PubMed:21732409, PubMed:26195725). It is acted on by 4 drugs in DrugBank.

Gene name
GPR18
UniProtKB entry
Q14330Swiss-Prot
Cellular location
Cell membrane
Residues / weight
331 residues · 38,133 Da
Also known as
G protein-coupled receptor 18 · GPCRW · NAGly receptor

Resolves to

Protein
UniProtQ14330UniProt nameGPR18_HUMAN
Gene
HGNCHGNC:4472NCBI Gene2841GenBank1066731GeneCardsGPR18
Pharmacology
IUPHAR/GtoPdb89KEGGhsa:2841
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which approved drugs act on N-arachidonyl glycine receptor, how selective are they, and which programs against it are still in active trials?

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