Glycine N-acyltransferase

BE0002305ProteinHumansGLYAT

Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. It is acted on by 2 drugs in DrugBank.

Gene name
GLYAT
UniProtKB entry
Q6IB77Swiss-Prot
Cellular location
Mitochondrion
Residues / weight
296 residues · 33,924 Da
Also known as
2.3.1.13 · AAc · ACGNAT · Acyl-CoA:glycine N-acyltransferase · Aralkyl acyl-CoA N-acyltransferase

Resolves to

Protein
UniProtQ6IB77UniProt nameGLYAT_HUMAN
Gene
HGNCHGNC:13734NCBI Gene10249GenBank2554941GeneCardsGLYAT
Pharmacology
KEGGhsa:10249
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glycine N-acyltransferase, how selective are they, and which programs against it are still in active trials?

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