Sodium- and chloride-dependent glycine transporter 2

BE0002310ProteinHumansSLC6A5

Sodium- and chloride-dependent glycine transporter (PubMed:10381548, PubMed:10606742, PubMed:16751771, PubMed:31370103, PubMed:9845349). It is acted on by 2 drugs in DrugBank.

Gene name
SLC6A5
UniProtKB entry
Q9Y345Swiss-Prot
Cellular location
Cell membrane
Residues / weight
797 residues · 87,433 Da
Also known as
GlyT-2 · GLYT2 · NET1 · Solute carrier family 6 member 5

Resolves to

Protein
UniProtQ9Y345UniProt nameSC6A5_HUMAN
Gene
HGNCHGNC:11051NCBI Gene9152GenBank4003525GeneCardsSLC6A5
Pharmacology
IUPHAR/GtoPdb936KEGGhsa:9152
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sodium- and chloride-dependent glycine transporter 2, how selective are they, and which programs against it are still in active trials?

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