All-trans-retinol 13,14-reductase

BE0002320ProteinHumansRETSAT

Catalyzes the saturation of all-trans-retinol to all-trans-13,14-dihydroretinol. It is acted on by 1 drug in DrugBank.

Gene name
RETSAT
UniProtKB entry
Q6NUM9Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
610 residues · 66,819 Da
Also known as
1.3.99.23 · All-trans-13,14-dihydroretinol saturase · PPAR-alpha-regulated and starvation-induced gene protein · PPSIG · RetSat

Resolves to

Protein
UniProtQ6NUM9UniProt nameRETST_HUMAN
Gene
HGNCHGNC:25991NCBI Gene54884GenBank37182258GeneCardsRETSAT
Pharmacology
KEGGhsa:54884
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which approved drugs act on All-trans-retinol 13,14-reductase, how selective are they, and which programs against it are still in active trials?

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