Retinol dehydrogenase 8

BE0002323ProteinHumansRDH8

Retinol dehydrogenase with a clear preference for NADP. It is acted on by 1 drug in DrugBank.

Gene name
RDH8
UniProtKB entry
Q9NYR8Swiss-Prot
Cellular location
Membrane
Residues / weight
311 residues · 33,755 Da
Also known as
1.1.1.300 · Photoreceptor outer segment all-trans retinol dehydrogenase · PRRDH · SDR28C2 · Short chain dehydrogenase/reductase family 28C member 2

Resolves to

Protein
UniProtQ9NYR8UniProt nameRDH8_HUMAN
Gene
HGNCHGNC:14423NCBI Gene50700GenBank7527474GeneCardsRDH8
Pharmacology
KEGGhsa:50700
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Retinol dehydrogenase 8, how selective are they, and which programs against it are still in active trials?

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