Calcitonin gene-related peptide 2

BE0002370ProteinHumansCALCB

CALCB/CGRP2 is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex (PubMed:1318039, PubMed:9620797). It is acted on by 4 drugs in DrugBank.

Gene name
CALCB
UniProtKB entry
P10092Swiss-Prot
Cellular location
Secreted
Residues / weight
127 residues · 13,706 Da
Also known as
Beta-CGRP · Beta-type CGRP · CALC2 · Calcitonin gene-related peptide II · CGRP-II

Resolves to

Protein
UniProtP10092UniProt nameCALCB_HUMAN
Gene
HGNCHGNC:1438NCBI Gene797GeneCardsCALCB
Pharmacology
KEGGhsa:797
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Calcitonin gene-related peptide 2, how selective are they, and which programs against it are still in active trials?

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