Phosphatidylinositol 3-kinase regulatory subunit gamma

BE0002384ProteinHumansPIK3R3

Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. It is acted on by 1 drug in DrugBank.

Gene name
PIK3R3
UniProtKB entry
Q92569Swiss-Prot
Residues / weight
461 residues · 54,448 Da
Also known as
p55PIK · Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma · PI3-kinase regulatory subunit gamma · PI3-kinase subunit p55-gamma · PI3K regulatory subunit gamma

Resolves to

Protein
UniProtQ92569UniProt nameP55G_HUMAN
Gene
HGNCHGNC:8981NCBI Gene8503GeneCardsPIK3R3
Pharmacology
KEGGhsa:8503
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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10GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Phosphatidylinositol 3-kinase regulatory subunit gamma, and which indications are they being tested in?

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