Potassium voltage-gated channel subfamily KQT member 5

BE0002400ProteinHumansKCNQ5

Pore-forming subunit of the voltage-gated potassium (Kv) channel broadly expressed in brain and involved in the regulation of neuronal excitability (PubMed:10787416, PubMed:10816588, PubMed:11159685, PubMed:28669405). It is acted on by 4 drugs in DrugBank.

Gene name
KCNQ5
UniProtKB entry
Q9NR82Swiss-Prot
Cellular location
Cell membrane
Residues / weight
932 residues · 102,178 Da
Also known as
KQT-like 5 · Potassium channel subunit alpha KvLQT5 · Voltage-gated potassium channel subunit Kv7.5

Resolves to

Protein
UniProtQ9NR82UniProt nameKCNQ5_HUMAN
Gene
HGNCHGNC:6299NCBI Gene56479GeneCardsKCNQ5
Pharmacology
IUPHAR/GtoPdb564KEGGhsa:56479
Structure
PDB6B8QPDB9J38PDB9LIZ
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Potassium voltage-gated channel subfamily KQT member 5, how selective are they, and which programs against it are still in active trials?

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