P2Y purinoceptor 2

BE0002401ProteinHumansP2RY2

Receptor for ATP and UTP coupled to G proteins that activate a phosphatidylinositol-calcium second messenger system. It is acted on by 5 drugs in DrugBank.

Gene name
P2RY2
UniProtKB entry
P41231Swiss-Prot
Cellular location
Cell membrane
Residues / weight
377 residues · 42,273 Da
Also known as
ATP receptor · P2RU1 · P2U purinoceptor 1 · P2U receptor 1 · P2U1

Resolves to

Protein
UniProtP41231UniProt nameP2RY2_HUMAN
Gene
HGNCHGNC:8541NCBI Gene5029GeneCardsP2RY2
Pharmacology
IUPHAR/GtoPdb324KEGGhsa:5029
Structure
PDB9K0XPDB9K20PDB9K25
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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26+ReferencesStructured and connected to the statements they support
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Which compounds in development act on P2Y purinoceptor 2, and which indications are they being tested in?

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