DNA repair protein RAD51 homolog 1

BE0002412ProteinHumansRAD51

Homologous DNA recombinase that catalyzes strand exchange, a key step in DNA repair through homologous recombination (HR) (PubMed:12205100, PubMed:12442171, PubMed:15937124, PubMed:17515904, PubMed:17515903, PubMed:18417535, PubMed:19303847, PubMed:20231364, PubMed:20348101, PubMed:22325354, PubMed:23509288, PubMed:23754376, PubMed:24141787, PubMed:26681308, PubMed:27941124, PubMed:28575658, PubMed:32640219, PubMed:37499663,... It is acted on by 2 drugs in DrugBank.

Gene name
RAD51
UniProtKB entry
Q06609Swiss-Prot
Cellular location
Chromosome
Residues / weight
339 residues · 36,966 Da
Also known as
3.6.4.- · hRAD51 · HsRAD51 · RAD51 homolog A · RAD51A

Resolves to

Protein
UniProtQ06609UniProt nameRAD51_HUMAN
Gene
HGNCHGNC:9817NCBI Gene5888GeneCardsRAD51
Pharmacology
KEGGhsa:5888
Structure
PDB1B22PDB1N0WPDB5H1B
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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13Clinical trialsTrials of drugs acting on it, by phase and status
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30GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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45+ReferencesStructured and connected to the statements they support
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Which compounds in development act on DNA repair protein RAD51 homolog 1, and which indications are they being tested in?

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