Neuropeptide Y receptor type 1

BE0002451ProteinHumansNPY1R

Receptor for neuropeptide Y (NPY) and peptide YY (PYY) (PubMed:1317848, PubMed:1321422, PubMed:35165283, PubMed:35507650, PubMed:38882210). It is acted on by 3 drugs in DrugBank.

Gene name
NPY1R
UniProtKB entry
P25929Swiss-Prot
Cellular location
Cell membrane
Residues / weight
384 residues · 44,392 Da
Also known as
NPY1-R · NPYR · NPYY1

Resolves to

Protein
UniProtP25929UniProt nameNPY1R_HUMAN
Gene
HGNCHGNC:7956NCBI Gene4886GeneCardsNPY1R
Pharmacology
IUPHAR/GtoPdb305KEGGhsa:4886
Structure
PDB5ZBHPDB5ZBQPDB7VGX
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Neuropeptide Y receptor type 1, how selective are they, and which programs against it are still in active trials?

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