Plasma protease C1 inhibitor

BE0002458ProteinHumansSERPING1

Serine protease inhibitor, which acrs as a regulator of the classical complement pathway (PubMed:10946292, PubMed:11527969, PubMed:3458172, PubMed:6416294). It is acted on by 4 drugs in DrugBank.

Gene name
SERPING1
UniProtKB entry
P05155Swiss-Prot
Cellular location
Secreted
Residues / weight
500 residues · 55,154 Da
Also known as
C1 esterase inhibitor · C1 Inh · C1-inhibiting factor · C1IN · C1Inh

Resolves to

Protein
UniProtP05155UniProt nameIC1_HUMAN
Gene
HGNCHGNC:1228NCBI Gene710GeneCardsSERPING1
Pharmacology
KEGGhsa:710
Structure
PDB2OAYPDB5DU3PDB5DUQ
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
5Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
7GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
49+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Plasma protease C1 inhibitor, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In