D-alanyl-D-alanine carboxypeptidase DacA

BE0002475ProteinEscherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)dacA

Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. It is acted on by 1 drug in DrugBank.

Gene name
dacA
UniProtKB entry
P0AEB3Swiss-Prot
Cellular location
Cell inner membrane
Residues / weight
403 residues · 44,444 Da
Also known as
3.4.16.4 · DD-carboxypeptidase · PBP-5 · Penicillin-binding protein 5

Resolves to

Protein
UniProtP0AEB3UniProt nameDACA_ECOL6
Pharmacology
KEGGecc:c0722
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on D-alanyl-D-alanine carboxypeptidase DacA, and which indications are they being tested in?

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