N-terminal kinase-like protein

BE0002479ProteinHumansSCYL1

Regulates COPI-mediated retrograde protein traffic at the interface between the Golgi apparatus and the endoplasmic reticulum (PubMed:18556652). It is acted on by 1 drug in DrugBank.

Gene name
SCYL1
UniProtKB entry
Q96KG9Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Residues / weight
808 residues · 89,631 Da
Also known as
Coated vesicle-associated kinase of 90 kDa · CVAK90 · GKLP · NTKL · SCY1-like protein 1

Resolves to

Protein
UniProtQ96KG9UniProt nameSCYL1_HUMAN
Gene
HGNCHGNC:14372NCBI Gene57410GeneCardsSCYL1
Pharmacology
KEGGhsa:57410
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which approved drugs act on N-terminal kinase-like protein, how selective are they, and which programs against it are still in active trials?

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