DNA polymerase III subunit epsilon

BE0002492ProteinEscherichia coli (strain K12)dnaQ

DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. It is acted on by 2 drugs in DrugBank.

Gene name
dnaQ
UniProtKB entry
P03007Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
243 residues · 27,099 Da
Also known as
2.7.7.7 · mutD

Resolves to

Protein
UniProtP03007UniProt nameDPO3E_ECOLI
Gene
NCBI Gene946441
Pharmacology
KEGGecj:JW0205
Structure
PDB1J53PDB1J54PDB1MGZ
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which compounds in development act on DNA polymerase III subunit epsilon, and which indications are they being tested in?

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