Peptide deformylase

BE0002536ProteinStreptococcus pneumoniae (strain ATCC BAA-255 / R6)def

Removes the formyl group from the N-terminal Met of newly synthesized proteins. It is acted on by 3 drugs in DrugBank.

Gene name
def
UniProtKB entry
Q8DP79Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
203 residues · 22,692 Da
Also known as
3.5.1.88 · PDF · Polypeptide deformylase

Resolves to

Protein
UniProtQ8DP79UniProt nameDEF_STRR6
Gene
NCBI Gene934523
Pharmacology
KEGGspr:spr1310
Structure
PDB2AI7PDB2AIAPDB2AIE
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
3GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
4+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Peptide deformylase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In