Glyceraldehyde-3-phosphate dehydrogenase

BE0002606ProteinGeobacillus stearothermophilusgap

Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. It is acted on by 1 drug in DrugBank.

Gene name
gap
UniProtKB entry
P00362Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
335 residues · 36,075 Da
Also known as
1.2.1.12 · GAPDH · NAD-dependent glyceraldehyde-3-phosphate dehydrogenase

Resolves to

Protein
UniProtP00362UniProt nameG3P_GEOSE
Structure
PDB1DBVPDB1GD1PDB1NPT
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Glyceraldehyde-3-phosphate dehydrogenase, and which indications are they being tested in?

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