Guanylate kinase

BE0002642ProteinMycobacterium tuberculosisgmk

Essential for recycling GMP and indirectly, cGMP. It is acted on by 1 drug in DrugBank.

Gene name
gmk
UniProtKB entry
P9WKE9Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
208 residues · 22,095 Da
Also known as
2.7.4.8 · GMP kinase

Resolves to

Protein
UniProtP9WKE9UniProt nameKGUA_MYCTU
Gene
NCBI Gene886787
Pharmacology
KEGGmtu:Rv1389
Structure
PDB1S4QPDB1Z8FPDB1ZNW
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Guanylate kinase, how selective are they, and which programs against it are still in active trials?

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