FEZ-1 protein

Details

Name
FEZ-1 protein
Kind
protein
Synonyms
Not Available
Gene Name
blaFEZ-1
UniProtKB Entry
Q9K578TrEMBL
Organism
Fluoribacter gormanii
NCBI Taxonomy ID
464
Amino acid sequence
>lcl|BSEQ0011903|FEZ-1 protein
MKKVLSLTALMMVLNHSSFAYPMPNPFPPFRIAGNLYYVGTDDLASYLIVTPRGNILINS
DLEANVPMIKASIKKLGFKFSDTKILLISHAHFDHAAGSELIKQQTKAKYMVMDEDVSVI
LSGGKSDFHYANDSSTYFTQSTVDKVLHDGERVELGGTVLTAHLTPGHTRGCTTWTMKLK
DHGKQYQAVIIGSIGVNPGYKLVDNITYPKIAEDYKHSIKVLESMRCDIFLGSHAGMFDL
KNKYVLLQKGQNNPFVDPTGCKNYIEQKANDFYTELKKQETA
Number of residues
282
Molecular Weight
31464.995
Theoretical pI
8.68
GO Classification
Functions
metal ion binding
General Function
Not Available
Specific Function
beta-lactamase activity
Pfam Domain Function
Signal Regions
1-20
Transmembrane Regions
Not Available
Cellular Location
Not Available
Gene sequence
>lcl|BSEQ0005281|849 bp
ATGAAAAAAGTATTAAGTTTAACCGCATTGATGATGGTATTGAACCATTCAAGCTTCGCA
TATCCAATGCCAAATCCTTTTCCCCCATTCCGTATTGCTGGAAACTTGTACTATGTAGGC
ACTGATGATCTCGCAAGCTACCTGATTGTCACACCGAGAGGGAACATTTTGATCAATAGT
GATCTTGAGGCTAATGTTCCCATGATTAAAGCAAGTATAAAAAAACTAGGTTTTAAATTC
AGTGATACTAAAATTTTGCTGATTAGCCATGCTCATTTTGATCATGCGGCCGGTAGCGAA
TTAATTAAGCAACAAACAAAAGCAAAATATATGGTTATGGACGAGGATGTTTCGGTGATC
CTGTCTGGCGGTAAATCTGATTTTCATTATGCTAATGATTCCAGTACTTATTTTACTCAG
AGTACTGTGGATAAGGTTCTTCACGACGGAGAACGGGTGGAATTAGGAGGGACCGTATTA
ACTGCTCATTTGACTCCTGGACACACTAGAGGCTGTACCACCTGGACAATGAAACTAAAA
GATCACGGCAAGCAATATCAGGCCGTAATTATAGGAAGTATTGGCGTAAATCCTGGGTAT
AAATTGGTTGATAATATAACTTATCCAAAAATTGCCGAAGATTATAAGCACTCCATAAAG
GTACTTGAGTCAATGCGTTGCGATATTTTTCTAGGATCGCATGCCGGAATGTTTGATCTG
AAGAATAAATATGTACTATTACAAAAAGGTCAAAACAATCCCTTTGTTGATCCCACAGGC
TGTAAAAATTATATTGAACAAAAGGCAAACGATTTTTACACAGAACTTAAGAAGCAAGAA
ACTGCCTAA
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDQ9K578
UniProtKB Entry NameQ9K578_9GAMM
GenBank Gene IDY17896
PDB ID(s)1JT1, 1K07, 1L9Y
General References
  1. Garcia-Saez I, Mercuri PS, Papamicael C, Kahn R, Frere JM, Galleni M, Rossolini GM, Dideberg O: Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril. J Mol Biol. 2003 Jan 24;325(4):651-60. [Article]

Associated Data

Drug Relations
DrugDrug groupPharmacological action?TypeActionsDetails
EpicaptoprilexperimentalunknowntargetDetails