Apocarotenoid-15,15'-oxygenase

BE0002716ProteinSynechocystis sp. (strain PCC 6803 / Kazusa)

Cleaves a number of carotenals and carotenols in the all-trans configuration at the 15-15' double bond producing retinal or retinol, respectively. It is acted on by 2 drugs in DrugBank.

UniProtKB entry
P74334Swiss-Prot
Residues / weight
490 residues · 54,286 Da
Also known as
8'-apo-beta-carotenal 15,15'-oxygenase · ACO · Diox1

Resolves to

Protein
UniProtP74334UniProt nameACOX_SYNY3
Structure
PDB2BIWPDB2BIXPDB4OU8
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Apocarotenoid-15,15'-oxygenase, and which indications are they being tested in?

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