Kynureninase

BE0002732ProteinPseudomonas fluorescenskynU

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. It is acted on by 1 drug in DrugBank.

Gene name
kynU
UniProtKB entry
P83788Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
416 residues · 45,905 Da
Also known as
3.7.1.3 · L-kynurenine hydrolase

Resolves to

Protein
UniProtP83788UniProt nameKYNU_PSEFL
Structure
PDB1QZ9
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Kynureninase, and which indications are they being tested in?

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